منابع مشابه
Aging: Seeking Mitonuclear Balance
Metabolic imbalances accompany the aging process in many organisms, and signaling mechanisms that allay or prevent these imbalances can extend lifespan. Two recent studies by Auwerx and colleagues, including one in this issue, identify a conserved signaling network centered on mitochondrial stress responses that promotes longevity in response to changes in mitochondrial translation and NAD(+) m...
متن کاملThe mitonuclear compatibility hypothesis of sexual selection.
Why females assess ornaments when choosing mates remains a central question in evolutionary biology. We hypothesize that the imperative for a choosing female to find a mate with nuclear oxidative phosphorylation (OXPHOS) genes that are compatible with her mitochondrial OXPHOS genes drives the evolution of ornaments. Indicator traits are proposed to signal the efficiency of OXPHOS function thus ...
متن کاملMitonuclear linkage disequilibrium in human populations.
There is extensive evidence from model systems that disrupting associations between co-adapted mitochondrial and nuclear genotypes can lead to deleterious and even lethal consequences. While it is tempting to extrapolate from these observations and make inferences about the human-health effects of altering mitonuclear associations, the importance of such associations may vary greatly among spec...
متن کاملFishing for adaptive epistasis using mitonuclear interactions
Mitochondria provide us with the energy to get up and do what needs to be done. They do this with 37 genes encoded in their own genome and more than 1,200 genes from the nuclear genome, whose gene products are targeted to mitochondria after being translated on cytosolic ribosomes. This complex intergenomic communication is a hallmark of eukaryotic life and has been under continuous refinement f...
متن کاملFractal Population Ecology Theory
Abstract Purpose - The aim of this paper is to describe the population ecology theory through fractal thinking, an emergent human operating system that is creative, adaptive, healthy, and evolutionary; furthermore, a parallel is drawn between the population ecology model and the fractal structure. Top-down hierarchies are typically characterized by command and control systems of the authority t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Biology and Evolution
سال: 2015
ISSN: 0737-4038,1537-1719
DOI: 10.1093/molbev/msv104